Protein Modification Reagents
Medchemexpress LLC Hydroxy-PEG4-CH2COOH | 70678-95-4 | 97.0% | C10H20O7 | 100 MG
Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker essential for the synthesis of PROTACs. These molecules are designed with two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This design enables the selective degradation of target proteins by harnessing the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Essential for PROTAC synthesis
- Features two distinct ligands connected by a linker
- Targets an E3 ubiquitin ligase
- Binds to a specific target protein
- Enables selective degradation of target proteins
- Utilizes the ubiquitin-proteasome system
Sigma Aldrich Fine Chemicals Biosciences Trypsin from bovine pancreas TPCK Treated, essentially salt-free, lyophilized powder, >=10,000 BAEE units/mg protein | 9002-07-7 | MFCD00082094 | 500MG
Trypsin from bovine pancreas TPCK Treated, essentially salt-free, lyophilized powder, >=10,000 BAEE units/mg protein | 9002-07-7 | MFCD00082094 | 500MG
eMolecules 2055103-66-5 | Carboxyrhodamine 110-PEG4-alkyne | Broadpharm | MFCD30458035 | 587.629 | C32H33N3O8 | 85.000 | Nc1ccc2c(-c3ccc(cc3C(O)=O)C(=O)NCCOCCOCCOCCOCC#C)c3ccc(=N)cc3oc2c1 | 25mg | 340377112
Carboxyrhodamine 110-PEG4-alkyne | Broadpharm | 2055103-66-5 | MFCD30458035 | 587.629 | C32H33N3O8 | 85.000 | Nc1ccc2c(-c3ccc(cc3C(O)=O)C(=O)NCCOCCOCCOCCOCC#C)c3ccc(=N)cc3oc2c1 | 25mg | 340377112
![eMolecules 2107272-96-6 | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | Broadpharm870.450 | C44H63ClF3N3O9 | 97.000 | [Cl-].OC(=O)C(F)(F)F.COCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 298819349](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203362.JPG-250.jpg)
eMolecules 2107272-96-6 | N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | Broadpharm870.450 | C44H63ClF3N3O9 | 97.000 | [Cl-].OC(=O)C(F)(F)F.COCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 298819349
N-(m-PEG4)-N'-(amino-PEG3)-Cy5, TFA salt | Broadpharm | 2107272-96-6870.450 | C44H63ClF3N3O9 | 97.000 | [Cl-].OC(=O)C(F)(F)F.COCCOCCOCCOCCN1\C(=C\C=C\C=C\C2=[N+](CCOCCOCCOCCN)c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 298819349
Medchemexpress LLC Mal-PEG4-bis-PEG4-propargyl | 1060.19 | C49H81N5O20 | 10 MG
Mal-PEG4-bis-PEG4-propargyl is a polyethylene glycol (PEG) based, cleavable linker designed for bioconjugation and antibody-drug conjugate (ADC) assembly. It features a thiol-reactive maleimide and an alkyne (propargyl) handle to enable both thiol conjugation and copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry, providing flexibility for payload attachment and linker assembly.
- Cleavable 8-unit PEG spacer for improved solubility and flexibility.
- Maleimide group for selective thiol conjugation to cysteine residues.
- Propargyl (alkyne) handle for CuAAC click chemistry.
- Suitable for synthesis of antibody-drug conjugates and other bioconjugates.
- Supplied as a 10 mg package for research-scale use.
Medchemexpress LLC Biotin-PEG4-NHS ester | 459426-22-3 | 99.56% | C25H40N4O10S | 50 MG
Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker. It can be used in the synthesis of PROTACs for research purposes only.
- Biotin-labeled, PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
Medchemexpress LLC Dota-PEG5-azide | 3104986-47-9 | 98.0% | C28H52N8O12 | 50 MG
DOTA-PEG5-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent containing an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Functions as a click chemistry reagent
- Contains an azide group
- Enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing alkyne groups
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Medchemexpress LLC Biotin-PEG4-TFP ester | 2985664-57-9 | 97.8% | C27H37F4N3O8S | 100 MG
Biotin-PEG4-TFP ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Creative Biomart Albiglutide, Recombinant GLP1
The product is a dipeptidyl peptidase-4-resistant glucagon-like peptide-1 dimer fused to human albumin.